Choline kinase—more than a cancer therapy target?
نویسندگان
چکیده
منابع مشابه
Choline kinase as a precision medicine target for therapy in cancer, autoimmune diseases and malaria
Cancer cells have an altered metabolism that provides advantages to support unregulated growth and higher duplication rates. Among these critical changes, energy generation through aerobic glycolysis as well as increased glutamine catabolism, are essential components associated with altered levels of specific metabolites. Up-regulation of lipid metabolism also occurs frequently in cancer cells....
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2014
ISSN: 1759-4790,1759-4804
DOI: 10.1038/nrrheum.2014.180